5-(6-Chloro-2-morpholin-4-ylpyrimidin-4-yl)pyridin-2-ylamine → HCID 178486065, compound

HRID 2018837Notes

Reaction equation

HRID 2018837 reaction equation
[CH3:1][N:2]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[C@H:3]1[CH2:7][C@H:5]([NH2:6])[CH2:4]1.[NH2:15][c:16]1[n:21][cH:20][c:19]([c:22]2[n:27][c:26]([N:28]3[CH2:33][CH2:32][O:31][CH2:30][CH2:29]3)[n:25][c:24](Cl)[cH:23]2)[cH:18][cH:17]1>>[CH3:1][N:2]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[C@H:3]1[CH2:7][C@H:5]([NH:6][c:24]2[n:25][c:26]([N:28]3[CH2:33][CH2:32][O:31][CH2:30][CH2:29]3)[n:27][c:22]([c:19]4[cH:20][n:21][c:16]([NH2:15])[cH:17][cH:18]4)[cH:23]2)[CH2:4]1

Participants

7

Reactant 2

HCID 595075305-(6-Chloro-2-morpholin-4-ylpyrimidin-4-yl)pyridin-2-ylamineHCID 178486064HCID 178486064, compound

Product 1

HCID 178486065HCID 178486065, compound

Reagents, catalysts & solvents 4

HCID 23683543Potassium t-amylateReagentHCID 178492614HCID 178492614, compoundCatalystHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-f727e1880ab548a398dbee91529ba990
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…