2-Iodopyridine → HCID 178505983, compound

HRID 2018866Notes

Reaction equation

HRID 2018866 reaction equation
I[c:1]1[n:6][cH:5][cH:4][cH:3][cH:2]1.OB([c:7]1[c:13]([F:14])[cH:12][n:11][c:9]([Br:10])[cH:8]1)O>>[F:14][c:13]1[c:7]([c:1]2[n:6][cH:5][cH:4][cH:3][cH:2]2)[cH:8][c:9]([Br:10])[n:11][cH:12]1

Participants

7

Reactant 2

HCID 2211262-IodopyridineHCID 44631046(2-Bromo-5-fluoropyridin-4-yl)boronic acid

Product 1

HCID 178505983HCID 178505983, compound

Reagents, catalysts & solvents 4

HCID 11430Potassium CarbonateReagentHCID 75537289[1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethaneCatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
55 °C

Sources & evidence

ORD record
ord-d1f8a53c6f44417ab3f7512a906db5d5
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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