HCID 178418936, compound → HCID 178494107, compound

HRID 2019139Notes

Reaction equation

HRID 2019139 reaction equation
[CH3:1][O:2][c:3]1[c:8]([c:9]2[cH:25][c:14]([O:15][CH:16]([c:18]3[c:24](Cl)[n:23][cH:22][c:20]([F:21])[cH:19]3)[CH3:17])[c:12]([NH2:13])[n:11][cH:10]2)[cH:7][cH:6][cH:5][n:4]1.[cH:26]1[n:30][n:29][nH:28][cH:27]1>>[CH3:1][O:2][c:3]1[c:8]([c:9]2[cH:25][c:14]([O:15][CH:16]([c:18]3[c:24]([n:28]4[n:29][n:30][cH:26][cH:27]4)[n:23][cH:22][c:20]([F:21])[cH:19]3)[CH3:17])[c:12]([NH2:13])[n:11][cH:10]2)[cH:7][cH:6][cH:5][n:4]1

Participants

8

Reactant 2

HCID 178418936HCID 178418936, compoundHCID 178494108HCID 178494108, compound

Product 1

HCID 178494107HCID 178494107, compound

Reagents, catalysts & solvents 5

HCID 10796Cesium carbonateReagentHCID 167845palladium(II) acetateCatalystHCID 12010824Cy-vBRIDPCatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-0eddb9bdc6e440bab57c7a9fe18d7e4c
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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