Potassium Cation → 4-(4-Chloro-2-fluorophenoxy)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazoline
Reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[CH3:36][N:37]1[CH2:38][CH2:39][N:40]([CH2:43][CH2:44][CH2:45][O:46][S:47]([c:48]2[cH:49][cH:50][c:51]([CH3:52])[cH:53][cH:54]2)(=[O:55])=[O:56])[CH2:41][CH2:42]1.[Cl:8][c:9]1[cH:10][c:11]([F:29])[c:12]([O:13][c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([OH:26])[c:21]([O:24][CH3:25])[cH:22][c:23]23)[cH:27][cH:28]1.[K+:34].[K+:35].[O:57]=[CH:58][N:59]([CH3:60])[CH3:61].[OH2:62].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[Cl:8][c:9]1[cH:10][c:11]([F:29])[c:12]([O:13][c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:26][CH2:45][CH2:44][CH2:43][N:40]4[CH2:39][CH2:38][N:37]([CH3:36])[CH2:42][CH2:41]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[cH:27][cH:28]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d13462c1587c4008891708cf2711bb4f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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