N-(6-bromopyridazin-3-yl)-2-pyridin-2-ylacetamide → HCID 118484192, compound

HRID 2019390Notes

Reaction equation

HRID 2019390 reaction equation
CC1(C(C)(C)OB([CH:1]2[CH2:6][C:4](=[O:5])[CH2:3][CH2:2]2)O1)C.Br[c:7]1[n:22][n:21][c:10]([NH:11][C:12]([CH2:14][c:15]2[n:20][cH:19][cH:18][cH:17][cH:16]2)=[O:13])[cH:9][cH:8]1>>[O:13]=[C:12]([NH:11][c:10]1[n:21][n:22][c:7]([CH:1]2[CH2:6][C:4](=[O:5])[CH2:3][CH2:2]2)[cH:8][cH:9]1)[CH2:14][c:15]3[n:20][cH:19][cH:18][cH:17][cH:16]3

Participants

8

Reactant 2

HCID 118484205N-(6-bromopyridazin-3-yl)-2-pyridin-2-ylacetamideHCID 124704658HCID 124704658, compound

Product 1

HCID 118484192HCID 118484192, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 25953Cesium fluorideReagentHCID 86278421[1,1'-bis(di-tert-butylphosphino) ferrocene]dichloropalladium(II)CatalystHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
90 °C

Sources & evidence

ORD record
ord-97d9bdeddaed4cb28c86aad0f2e801fa
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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