4-Benzyloxy-phenylboronic acid → HCID 178489175, compound

HRID 2020777Notes

Reaction equation

HRID 2020777 reaction equation
[CH3:1][O:2][c:3]1[cH:8][cH:7][c:6]([c:9]2[c:13](Cl)[c:12]([C:14]([F:17])([F:16])[F:15])[o:11][n:10]2)[cH:5][cH:4]1.OB([c:18]1[cH:31][cH:30][c:21]([O:22][CH2:23][c:24]2[cH:29][cH:28][cH:27][cH:26][cH:25]2)[cH:20][cH:19]1)O>>[CH3:1][O:2][c:3]1[cH:8][cH:7][c:6]([c:9]2[c:13]([c:18]3[cH:31][cH:30][c:21]([O:22][CH2:23][c:24]4[cH:29][cH:28][cH:27][cH:26][cH:25]4)[cH:20][cH:19]3)[c:12]([C:14]([F:17])([F:16])[F:15])[o:11][n:10]2)[cH:5][cH:4]1

Participants

8

Reactant 2

HCID 27343144-Benzyloxy-phenylboronic acidHCID 178489176HCID 178489176, compound

Product 1

HCID 178489175HCID 178489175, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 516892Sodium BicarbonateReagentHCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-a8fdf9a9d5754dc58b4d2d8f4ced9115
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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