tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate → HCID 178494105, compound

HRID 2022116Notes

Reaction equation

HRID 2022116 reaction equation
[CH3:1][O:2][c:3]1[c:8](Br)[cH:7][cH:6][cH:5][n:4]1.[CH3:9][C:10]([O:13][C:14]([N:16]1[C:20](=[O:21])[CH:19]=[CH:18][CH2:17]1)=[O:15])([CH3:12])[CH3:11]>>[CH3:1][O:2][c:3]1[c:8]([C:18]([CH2:17][N:16]([C:14]([O:13][C:10]([CH3:12])([CH3:11])[CH3:9])=[O:15])[C:20]2=[O:21])=[CH:19]2)[cH:7][cH:6][cH:5][n:4]1

Participants

8

Reactant 2

HCID 11435337tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylateHCID 125333903-Bromo-2-methoxypyridine

Product 1

HCID 178494105HCID 178494105, compound

Reagents, catalysts & solvents 5

HCID 92796Silver carbonateReagentHCID 167845palladium(II) acetateCatalystHCID 178454858HCID 178454858, compoundCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
70 °C

Sources & evidence

ORD record
ord-3eaa853f58cc4d77bb4e57d2d00bc783
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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