Di-tert-butyl bicarbamate → HCID 178428597, compound

HRID 2022655Notes

Reaction equation

HRID 2022655 reaction equation
[CH3:1][C:2]([O:5][C:6]([NH:8][NH:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])=[O:7])([CH3:4])[CH3:3].[CH3:17][c:18]1[cH:23][c:22](Br)[n:21][cH:20][cH:19]1>>[CH3:17][c:18]1[cH:23][c:22]([N:8]([C:6]([O:5][C:2]([CH3:4])([CH3:3])[CH3:1])=[O:7])[NH:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[n:21][cH:20][cH:19]1

Participants

8

Reactant 2

HCID 85431Di-tert-butyl bicarbamateHCID 27340872-Bromo-4-methylpyridine

Product 1

HCID 178428597HCID 178428597, compound

Reagents, catalysts & solvents 5

HCID 23675099HCID 23675099, compoundReagentHCID 167845palladium(II) acetateCatalystHCID 634876Binap, (A+-)-CatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-ffa1612561d641ee8b34169312a35574
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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