Ethylene → 7-bromo-5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-one
Reaction equation
[CH2:1]=[CH2:2].CC(C(O[NH:3][C:4]([c:6]1[c:13]([Cl:14])[c:11]([Br:12])[cH:10][c:8]([Cl:9])[cH:7]1)=[O:5])=O)(C)C>>[Cl:9][c:8]1[c:7]([c:6]2[c:13]([Cl:14])[c:11]([Br:12])[cH:10]1)[CH2:2][CH2:1][NH:3][C:4]2=[O:5]Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 50 °C
Sources & evidence
- ORD record
- ord-fdacd21acbd54e9a8c5066b38dea67b2
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
Loading…