Acetylene → 4-Chloro-1,7-naphthyridin-8(7H)-one
Reaction equation
[CH:1]#[CH:2].CC(C(O[NH:3][C:4]([c:6]1[n:12][cH:11][cH:10][c:8]([Cl:9])[cH:7]1)=[O:5])=O)(C)C>>[Cl:9][c:8]1[c:7]([c:6]2[n:12][cH:11][cH:10]1)[CH:2]=[CH:1][NH:3][C:4]2=[O:5]Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 60 °C
Sources & evidence
- ORD record
- ord-d0948d9c3f14438abf551919c0a1446e
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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