Phenol → 1-tert-Butyl-4-phenoxybenzene

HRID 202521Notes

Reaction equation

HRID 202521 reaction equation
[C:19](=[O:20])([O-:21])[O-:22].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([Br:11])[cH:9][cH:10]1.[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[Cs+:23].[Cs+:24].[OH:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[OH:25][C:26]([c:27]1[c:28]2[c:29]([cH:30][cH:31][cH:32][cH:33]2)[cH:34][cH:35][cH:36]1)=[O:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([O:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:9][cH:10]1

Participants

8

Reactant 7

HCID 996PhenolHCID 1140TolueneHCID 68471-Naphthoic acidHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 775951-Bromo-4-tert-butylbenzeneHCID 104967Cesium cation2×

Product 1

HCID 2200481-tert-Butyl-4-phenoxybenzene

Sources & evidence

ORD record
ord-a122c7af66f24113aeffc923f148539a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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