PF-06767832 → HCID 178430576, compound

HRID 2030106Notes

Reaction equation

HRID 2030106 reaction equation
[CH3:1][c:2]1[c:7]([CH2:8][c:9]2[cH:14][cH:13][c:12]([c:15]3[n:19][cH:18][s:17][cH:16]3)[cH:11][cH:10]2)[cH:6][c:5]([C:20]([NH:22][C@@H:23]4[C@@H:28]([OH:29])[CH2:27][O:26][CH2:25][CH2:24]4)=[O:21])[n:4][cH:3]1>>[CH3:1][c:2]1[c:7]([C:8]([c:9]2[cH:14][cH:13][c:12]([c:15]3[n:19][cH:18][s:17][cH:16]3)[cH:11][cH:10]2)=O)[cH:6][c:5]([C:20]([NH:22][C@@H:23]4[C@@H:28]([OH:29])[CH2:27][O:26][CH2:25][CH2:24]4)=[O:21])[n:4][cH:3]1

Participants

8

Reactant 1

HCID 118663155PF-06767832

Product 1

HCID 178430576HCID 178430576, compound

Reagents, catalysts & solvents 6

HCID 795ImidazoleReagent2×HCID 6629Cumene HydroperoxideReagentHCID 178505965HCID 178505965, compoundCatalystHCID 111,2-DichloroethaneSolventHCID 6342AcetonitrileSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-b09745b6764b4f688b4ab77f3ca9d054
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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