Tetrahydrofuran → 1-(1,4-dioxaspiro[4.5]dec-8-yl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
Reaction equation
[I:1][c:2]1[n:3][nH:4][c:5]2[n:6][cH:7][n:8][c:9]([NH2:11])[c:10]12.[O:12]1[CH2:13][CH2:14][O:15][C:16]12[CH2:17][CH2:18][CH:19]([OH:22])[CH2:20][CH2:21]2.[O:42]=[C:43]([O:44][CH2:45][CH3:46])[N:47]=[N:48][C:49]([O:50][CH2:51][CH3:52])=[O:53].[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1.[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[I:1][c:2]1[n:3][n:4]([CH:19]2[CH2:18][CH2:17][C:16]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:21][CH2:20]2)[c:5]2[n:6][cH:7][n:8][c:9]([NH2:11])[c:10]12Participants
6
Sources & evidence
- ORD record
- ord-a840edabd45e4921a9585e98807389d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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