Hydrochloric Acid → N-(2-(2-(4-Hydroxy-4-(pyridin-4-ylmethyl)piperidin-1-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylphenylsulfonamide

HRID 203968Notes

Reaction equation

HRID 203968 reaction equation
[C:46](=[O:47])([OH:48])[O-:49].[CH2:51]([Cl:52])[Cl:53].[CH3:1][O:2][c:3]1[cH:4][c:5]([CH3:22])[c:6]([S:10](=[O:11])(=[O:12])[N:13]([CH3:14])[CH2:15][CH2:16][O:17][CH2:18][C:19](=[O:20])[OH:21])[c:7]([CH3:9])[cH:8]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[ClH:23].[ClH:24].[Na+:50].[n:25]1[cH:26][cH:27][c:28]([CH2:31][C:32]2([OH:38])[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2)[cH:29][cH:30]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH3:22])[c:6]([S:10](=[O:11])(=[O:12])[N:13]([CH3:14])[CH2:15][CH2:16][O:17][CH2:18][C:19](=[O:21])[N:35]2[CH2:34][CH2:33][C:32]([CH2:31][c:28]3[cH:27][cH:26][n:25][cH:30][cH:29]3)([OH:38])[CH2:37][CH2:36]2)[c:7]([CH3:9])[cH:8]1

Participants

8

Reactant 7

HCID 313Hydrochloric Acid2×HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 8471TriethylamineHCID 46870354{2-[(4-methoxy-2,6-dimethyl-benzenesulfonyl)-methyl-amino]-ethoxy}acetic AcidHCID 598200924-(Pyridin-4-ylmethyl)piperidin-4-ol

Product 1

HCID 59820090N-(2-(2-(4-Hydroxy-4-(pyridin-4-ylmethyl)piperidin-1-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylphenylsulfonamide

Sources & evidence

ORD record
ord-d94352e714fe43a7820335ee81d8da19
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…