反应详情

TEA (8.00 mL, 57.5 mmol) followed by pivaloyl chloride (2.80 mL, 22.8 mmol) in THF (25 mL) are added to 4-chloro-3-nitrobenzylamine (5.00 g) in THF (100 mL). The reaction mixture is diluted with THF and stirred at rt for 1.5 h. The mixture is filtered and washed and the filtrate is concentrated.

1. filtrationThe mixture is filtered
2. washwashed
3. concentrationthe filtrate is concentrated