反应详情

To a solution of 3,5-diethyl-4H-pyrazole (2.14 g, 17.2 mmol) (i.e. the product of Example 15, Step A) in N,N-dimethylformamide (10 mL) was added potassium carbonate (4.7 g) and ethyl bromoacetate (2.9 mL, 26.1 mmol). The reaction mixture was stirred at room temperature overnight. The resulting solids were filtered off and the filtrate was diluted with ethyl acetate, washed with water and dried over MgSO4. The reaction mixture was concentrated under reduced pressure to give 2.79 g of the title compound.

1. filtrationThe resulting solids were filtered off
2. additionthe filtrate was diluted with ethyl acetate
3. washwashed with water
4. dry with materialdried over MgSO4
5. concentrationThe reaction mixture was concentrated under reduced pressure