反应详情

7-(3-Hydroxyprop-1-ynyl)-3-(4-methoxyphenyl)chromen-2-one is hydrogenated to completion in THF on palladium/active carbon catalyst. The catalyst is filtered off, the solvent is removed in vacuo, and the crude product is recrystallised from toluene/heptane (1:1), giving 7-(3-hydroxypropyl)-3-(4-methoxyphenyl)chromen-2-one as colourless solid.

1. filtrationThe catalyst is filtered off
2. customthe solvent is removed in vacuo
3. customthe crude product is recrystallised from toluene/heptane (1:1)