Hydrochloric Acid → Tert-butyl 3-[[4-[2,2-dimethylpropyl(methyl)amino]-6-[2-methyl-5-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]pyrrolidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:13][c:14]2[n:15][c:16]([NH:21][c:22]3[c:23]([CH3:32])[cH:24][cH:25][c:26]([C:28]([NH:29][CH3:30])=[O:31])[cH:27]3)[cH:17][c:18]([F:20])[n:19]2)[CH2:11][CH2:12]1.[CH2:50]1[O:51][CH2:52][CH2:53][O:54][CH2:55]1.[CH3:34][NH:35][CH2:36][C:37]([CH3:38])([CH3:39])[CH3:40].[CH:41]([N:42]([CH2:43][CH3:44])[CH:45]([CH3:46])[CH3:47])([CH3:48])[CH3:49].[ClH:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:13][c:14]2[n:15][c:16]([NH:21][c:22]3[c:23]([CH3:32])[cH:24][cH:25][c:26]([C:28]([NH:29][CH3:30])=[O:31])[cH:27]3)[cH:17][c:18]([N:35]([CH3:34])[CH2:36][C:37]([CH3:38])([CH3:39])[CH3:40])[n:19]2)[CH2:11][CH2:12]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d0dc90fd5bd0496fafccac42be9ab024
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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