反应详情

5-(4-Chloro-phenyl)-cyclohexane-1,3-dione (1.0 g, 4.5 mmol) was suspended in N,N-dimethylformamide dimethylacetal (5 ml) and heated at reflux for 4 h. The reaction mixture was cooled to ambient temperature and the precipitate was filtered, washed with diethyl ether and dried under air suction. The required product was obtained as a yellow solid which was used in the next step without further purification.

1. temperatureheated
2. temperatureat reflux for 4 h
3. filtrationthe precipitate was filtered
4. washwashed with diethyl ether
5. customdried under air suction