反应详情

In analogy to the procedure described for the preparation of intermediate A-11 [C], (1-{(rac)-3-[5-chloro-3-fluoro-2-(2-methyl-2H-tetrazol-5-yl)-phenyl]-6,7-dihydro-5H-[1]pyrindin-7-ylcarbamoyl}-cyclopropyl)-carbamic acid tert-butyl ester (example 54) has been treated with trifluoroacetic acid (90%) to give the title compound as light brown amorphous solid. MS: 428.1 (MH+, 1Cl).