Phenethylamine → HCID 67182730, compound

HRID 2047612Notes

Reaction equation

HRID 2047612 reaction equation
[CH2:1](N)C1C=CC=CC=1.C(N)CC1C=CC=CC=1.[CH3:18][S:19][C:20]1[NH:25][C:24](=[O:26])[N:23]=[C:22]([C:27]2[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=2)[N:21]=1>>[CH3:1][N:25]1[C:20]([S:19][CH3:18])=[N:21][C:22]([C:27]2[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=2)=[N:23][C:24]1=[O:26]

Participants

4

Reactant 3

HCID 1001PhenethylamineHCID 7504BenzylamineHCID 178503394HCID 178503394, compound

Product 1

HCID 67182730HCID 67182730, compound

Procedure

By analogy with the method described in example 1 (step 1.2), using benzylamine (commercially available) in place of phenethylamine and 6-Methylsulfanyl-4-pyridin-4-yl-1H-[1,3,5]triazin-2-one (synthesis as described in U.S. Pat. No. 4,406,897) in place of 1-Methyl-6-methylsulfanyl-4-pyridin-4-yl-1H-[1,3,5]triazin-2-one, to afford the product which was transformed into the hyrdochloride salt in the usual manner to give 0.15 g (47%) of a white solid.

Workup

  1. customsynthesis

Sources & evidence

ORD record
ord-8d14367b23894262b88c8da607b34461
Source dataset
uspto-grants-2013_11
Patent number
US08592580B2

Reaction notes

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