Methyl Ethyl Ketone → HCID 85939531, compound

HRID 2049306Notes

Reaction equation

HRID 2049306 reaction equation
[Br-:1].[Br-:2].[C:3]1([OH:9])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:10](=[O:13])([O-])[O-].[K+].[K+].[CH2:16]([O:18][C:19](=[O:22])[CH2:20]Br)[CH3:17].[CH3:23][C:24]([CH2:26][CH3:27])=[O:25]>>[CH2:16]([O:18][C:19](=[O:22])[CH2:20][O:25][C:24]1[C:23]([Br:1])=[CH:5][C:4]([C:3]([C:8]2[O:13][CH:10]=[CH:6][CH:7]=2)=[O:9])=[CH:27][C:26]=1[Br:2])[CH3:17]

Participants

5

Reactant 4

HCID 6569Methyl Ethyl KetoneHCID 7748Ethyl bromoacetateHCID 11430Potassium CarbonateHCID 20345032Phenol dibromide

Product 1

HCID 85939531HCID 85939531, compound

Procedure

There was kept under reflux for 6 hours 300 ml of methylethylketone containing 21 g of the phenol of step (A), 15 g of potassium carbonate and 18 g of ethylbromoacetate. After hot filtration the solvent was evaporated and the solid recrystallised in ethanol. 21 g of the ester were obtained, which melted at 114° C.

Workup

  1. filtrationAfter hot filtration the solvent
  2. customwas evaporated
  3. customthe solid recrystallised in ethanol

Sources & evidence

ORD record
ord-55aee60d737a4efd80056fb1bc3e179f
Source dataset
uspto-grants-1980_04
Patent number
US04197309

Reaction notes

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