Hydrochloric Acid → HCID 85939535, compound

HRID 2049307Notes

Reaction equation

HRID 2049307 reaction equation
[C:1]1([C:6]([C:8]2[CH:18]=[C:17]([CH3:19])[C:11]([O:12][CH2:13][C:14]([OH:16])=[O:15])=[C:10]([CH3:20])[CH:9]=2)=O)[S:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:22][OH:23].Cl>N1C=CC=CC=1>[S:5]1[CH:4]=[CH:3][CH:2]=[C:1]1[C:6](=[N:22][OH:23])[C:8]1[CH:18]=[C:17]([CH3:19])[C:11]([O:12][CH2:13][C:14]([OH:16])=[O:15])=[C:10]([CH3:20])[CH:9]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 443297Hydroxyamine hydrochlorideHCID 53689654HCID 53689654, compound

Product 1

HCID 85939535HCID 85939535, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

4 g of 4-(2-thenoyl)-2,6-dimethyl-phenoxyacetic acid and 4 g of hydroxylamine hydrochloride were dissolved in 30 ml of pyridine and the mixture was kept for 3 hours at reflux. The mixture was then poured into an N aqueous solution of hydrochloric acid and the oxime extracted in ethyl ether. The remaining solid, after evaporation of the solvent, was a mixture of the two isomers of the oxime which melted at 152° C.

Workup

  1. temperatureat reflux
  2. extractionthe oxime extracted in ethyl ether
  3. customThe remaining solid, after evaporation of the solvent
  4. additiona mixture of the two isomers of the oxime which melted at 152° C.

Sources & evidence

ORD record
ord-c1ed5d3e0c974745ac143d21edf61556
Source dataset
uspto-grants-1980_04
Patent number
US04197309

Reaction notes

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