HCID 20344070, compound → HCID 20344086, compound

HRID 2049679Notes

Reaction equation

HRID 2049679 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[S:11][C:10]3[CH:18]=[CH:19][CH:20]=[CH:21][C:9]=3[C:8]2=[O:22])[CH2:4][CH2:3]1>O1CCCC1>[OH:22][CH:8]1[C:5]2([CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]2)[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[S:11][C:10]2[CH:18]=[CH:19][CH:20]=[CH:21][C:9]1=2

Participants

3

Reactant 1

HCID 20344070HCID 20344070, compound

Product 1

HCID 20344086HCID 20344086, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of 5.0 g of 10,11-dihydro-1'-methyl-11-oxospiro[dibenz(b,f)thiepin-10,4'-piperidine], free base of Example 8, in 40 ml of tetrahydrofuran is treated according to the procedure of Example 7 to provide 10,11-dihydro-11-hydroxy-1'-methylspiro[dibenz(b,f)thiepin-10,4'-piperidine].

Sources & evidence

ORD record
ord-6be04c30d9dc4c04b07c157347bc02d3
Source dataset
uspto-grants-1980_04
Patent number
US04198420

Reaction notes

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