Dabco → HCID 20344554, compound

HRID 2049825Notes

Reaction equation

HRID 2049825 reaction equation
[CH3:1][C:2](=[CH2:10])[CH2:3][O:4][CH2:5][C:6]([F:9])([F:8])[F:7].C1N2CCN(CC2)C1>C(O)C.O.CCCCC>[CH3:1][C:2]([CH3:10])=[CH:3][O:4][CH2:5][C:6]([F:9])([F:8])[F:7]

Participants

5

Reactant 2

HCID 9237DabcoHCID 11469181HCID 11469181, compound

Product 1

HCID 20344554HCID 20344554, compound

Reagents, catalysts & solvents 2

HCID 8003PentaneSolventHCID 19096565Water ethanolSolvent

Procedure

In 100 ml 20% ethanol/water is added 11 g (71.4 mmol) 2,2,2-trifluoroethyl 2-methyl-2-propenyl ether and 0.59 g (0.642 mmol) 1,4-diazobicyclo(2,2,2)octane. Rhodium tris-triphenylphosphine chloride (16 g, 142.8 mmol) is then added to the stirring mixture, and the solution is heated to 90° for 4 hr. The reaction is then cooled, brought up in pentane, filtered, washed with water and brine and dried over sodium sulfate. The crude product is distilled, yielding 2,2,2-trifluoroethyl 2-methyl-1-propenyl ether.

Workup

  1. temperaturethe solution is heated to 90° for 4 hr
  2. temperatureThe reaction is then cooled
  3. filtrationfiltered
  4. washwashed with water and brine
  5. dry with materialdried over sodium sulfate
  6. distillationThe crude product is distilled

Sources & evidence

ORD record
ord-229728219d4245fb8fcdc0a5635ffc18
Source dataset
uspto-grants-1980_04
Patent number
US04198527

Reaction notes

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