Hydrochloric Acid → HCID 19833991, compound

HRID 2050818Notes

Reaction equation

HRID 2050818 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:25])[O:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[ClH:26].CCCCCC>CO>[ClH:26].[CH:12]1[C:10]2[C:11]3[CH:1]=[CH:2][CH:3]=[CH:4][C:5]=3[CH2:6][N:7]([C:16](=[NH:25])[O:17][CH2:18][C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH2:8][C:9]=2[CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8058HexaneHCID 19833992HCID 19833992, compound

Product 1

HCID 19833991HCID 19833991, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
0 °C

Procedure

1.0 g of benzyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate is dissolved in 1 ml of methanol. The solution is cooled to 0° C. and treated with 0.6 ml of a 5N alcoholic hydrochloric acid solution. After stirring at 0°-5° C. for ten minutes, 10 ml of n-hexane are added, the precipitated product is removed by filtration under suction, and there is obtained benzyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate hydrochloride, m.p. 90°-92° C.

Workup

  1. customthe precipitated product is removed by filtration under suction

Sources & evidence

ORD record
ord-014c1c3751a74e55a64c0e84b280f990
Source dataset
uspto-grants-1991_05
Patent number
US05015640

Reaction notes

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