1,4-Dihydroxy-2,2,6,6-tetramethylpiperidine → HCID 67827820, compound

HRID 2050995Notes

Reaction equation

HRID 2050995 reaction equation
[C:1](Cl)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10](Cl)=[O:11].[OH:15][CH:16]1[CH2:21][C:20]([CH3:23])([CH3:22])[N:19]([O:24][CH3:25])[C:18]([CH3:27])([CH3:26])[CH2:17]1.[OH:28][CH:29]1[CH2:34][C:33]([CH3:36])([CH3:35])[N:32]([OH:37])[C:31]([CH3:39])([CH3:38])[CH2:30]1.C(N(CC)CC)C>C(Cl)Cl>[C:1]([O:15][CH:16]1[CH2:21][C:20]([CH3:22])([CH3:23])[N:19]([O:24][CH3:25])[C:18]([CH3:27])([CH3:26])[CH2:17]1)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([O:28][CH:29]1[CH2:34][C:33]([CH3:35])([CH3:36])[N:32]([OH:37])[C:31]([CH3:39])([CH3:38])[CH2:30]1)=[O:11]

Participants

6

Reactant 4

HCID 53951,4-Dihydroxy-2,2,6,6-tetramethylpiperidineHCID 8471TriethylamineHCID 66072Sebacoyl chlorideHCID 109977701-Methoxy-2,2,6,6-tetramethyl-piperidin-4-ol

Product 1

HCID 67827820HCID 67827820, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Sebacoyl chloride is added to a mixture of 4-hydroxy-1-methoxy-2,2,6,6-tetramethylpiperidine, 4-hydroxyl-1-oxyl-2,2,6,6-tetramethylpiperidine, triethylamine and methylene chloride. The reaction mixture is worked up in the usual manner and purified by flash chromatography on silica gel to afford the title compound.

Workup

  1. custompurified by flash chromatography on silica gel

Sources & evidence

ORD record
ord-2a179d901f994219952c061a6d4bc8d7
Source dataset
uspto-grants-1991_05
Patent number
US05015682

Reaction notes

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