Acetophenone → HCID 56638907, compound

HRID 2051053Notes

Reaction equation

HRID 2051053 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].CO[C:12](=[O:30])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]C.[CH3:31][O-].[Na+]>C1(C)C(C)=CC=CC=1>[C:1]([CH2:2][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][C:12]([CH3:31])=[O:30])(=[O:3])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 7410AcetophenoneHCID 8201Methyl StearateHCID 10942334Sodium Methoxide

Product 1

HCID 56638907HCID 56638907, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

Acetophenone (30 grams; 0.25 mol), methylstearate (298 grams; 1.0 mol), xylene (300 ml) and sodium methoxide (17.3 grams; 0.3 mol) were placed into a four-necked, round bottom one liter flask equipped a in Example 1. The mixture was heated with stirring to 135°-140° C. and maintained there for 6 hours under a blanket of nitrogen. The procedure set forth in Example 1 was used to recover the desired product, benzoylstearoylmethane (43 grams; 45 weight percent yield) having a purity of 95%.

Workup

  1. customequipped a in Example 1
  2. temperatureThe mixture was heated
  3. temperaturemaintained there for 6 hours under a blanket of nitrogen
  4. customto recover the desired product, benzoylstearoylmethane (43 grams; 45 weight percent yield)

Sources & evidence

ORD record
ord-4e4ee947668e49898e09ae8a6334f5e4
Source dataset
uspto-grants-1991_05
Patent number
US05015777

Reaction notes

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