Chloride → 4-chloro-N-[5-chloro-2-(2-methoxy-pyridine-3-carbonyl)-pyridin-3-yl]-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide

HRID 205109Notes

Reaction equation

HRID 205109 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:32][O:33][c:34]1[c:35]([C:36](=[O:37])[N:38]([O:39][CH3:40])[CH3:41])[cH:42][cH:43][cH:44][n:45]1.[CH:28]([Mg+:29])([CH3:30])[CH3:31].[Cl-:27]>>[c:2]1([C:36]([c:35]2[c:34]([O:33][CH3:32])[n:45][cH:44][cH:43][cH:42]2)=[O:37])[n:3][cH:4][c:5]([Cl:26])[cH:6][c:7]1[N:8]([S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]([C:19]([F:20])([F:21])[F:22])[c:15]([Cl:18])[cH:16][cH:17]1)[CH2:23][O:24][CH3:25]

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 45871212N,2-Dimethoxy-N-methylnicotinamideHCID 57942086N-(2-Bromo-5-chloro-pyridin-3-yl)-4-chloro-N-methoxvmethyl-3-trifluoromethyl-benzenesulfonamideHCID 178461726HCID 178461726, compound

Product 1

HCID 579425224-chloro-N-[5-chloro-2-(2-methoxy-pyridine-3-carbonyl)-pyridin-3-yl]-N-methoxymethyl-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-c9e5dac21ce04dffa0161e0d6b61e50b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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