Hydrogen Peroxide → HCID 14422495, compound

HRID 2051130Notes

Reaction equation

HRID 2051130 reaction equation
[Cl:1][C:2]1[N:3]=[C:4]2[N:8]([C:9]=1[S:10]([NH2:13])(=[O:12])=[O:11])[CH2:7][CH2:6][S:5]2=[O:14].[OH:15]O>C(O)(=O)C>[Cl:1][C:2]1[N:3]=[C:4]2[N:8]([C:9]=1[S:10]([NH2:13])(=[O:12])=[O:11])[CH2:7][CH2:6][S:5]2(=[O:15])=[O:14]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 14422494HCID 14422494, compound

Product 1

HCID 14422495HCID 14422495, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
100 °C

Procedure

To a suspension of 0.80 g of 6-chloro-2,3-dihydroimidazo[2,1-b]thiazole-5-sulfonamide-1-oxide in 10 ml of acetic acid is added 4 ml of 30% aqueous hydrogen peroxide solution followed by stirring for hour 100° C. After cooling, ice water is added to the reaction mixture to precipitate crystals. The crystals are collected by filtration, washed with water and dried to give 0.30 g of the title compound as colorless crystals. mp. 246°-247° C.

Workup

  1. temperatureAfter cooling
  2. customto precipitate crystals
  3. filtrationThe crystals are collected by filtration
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-d4f07f59fe0d482aae98f2a2b4a95b53
Source dataset
uspto-grants-1991_05
Patent number
US05017212

Reaction notes

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