Potassium Carbonate → HCID 20378049, compound

HRID 2051750Notes

Reaction equation

HRID 2051750 reaction equation
[O:1]=[C:2]([C:8]([O:10][CH2:11]C)=[O:9])[C:3]([O:5][CH2:6][CH3:7])=[O:4].Br[CH:14]([CH2:19][OH:20])[C:15]([O:17][CH3:18])=[O:16].[C:21](=O)([O-])[O-].[K+].[K+].C(=O)([O-])[O-]>CCCCCC>[O:20]1[CH2:19][CH:14]([C:15]([O:17][CH2:18][CH3:21])=[O:16])[O:1][C:2]1([C:3]([O:5][CH2:6][CH3:7])=[O:4])[C:8]([O:10][CH3:11])=[O:9]

Participants

6

Reactant 4

HCID 11430Potassium CarbonateHCID 19660Carbonate IonHCID 691051,3-Diethyl 2-oxopropanedioateHCID 11964350methyl 2-bromo-3-hydroxypropionate

Product 1

HCID 20378049HCID 20378049, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Diethyl ketomalonate 15 g (0.086 mol) and methyl 2-bromo-3-hydroxy-propionate (Example 5a)) were mixed and after returning to room temperature were treated with hexane (50 ml) and 18.6 g (0.134 mol) potassium carbonate. After 6 hours an additional 5.9 g of carbonate was added and the mixture stirred at 45° overnight.

Workup

  1. customafter returning to room temperature

Sources & evidence

ORD record
ord-893dd06d89e24067b08d88b1936011f1
Source dataset
uspto-grants-1980_01
Patent number
US04182718

Reaction notes

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