Diethanolamine → HCID 20378131, compound

HRID 2051854Notes

Reaction equation

HRID 2051854 reaction equation
[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[Cl:8][CH2:9][CH2:10][N:11]=[C:12]=[O:13]>O1CCCC1>[Cl:8][CH2:9][CH2:10][NH:11][C:12]([N:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4])=[O:13]

Participants

4

Reactant 2

HCID 8113DiethanolamineHCID 160352-Chloroethyl isocyanate

Product 1

HCID 20378131HCID 20378131, compoundYield 100.2%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2.1 g of diethanolamine are dissolved in 30 ml of tetrahydrofuran, and 2.1 g of 2-chloroethyl isocyanate is added dropwise thereto at 0° to 5° C. The solution is stirred at room temperature for 2 hours. Then, the reaction solution is condensed under reduced pressure. 4.2 g of 1-(2-chloroethyl)-3,3-bis(2-hydroxyethyl)urea are obtained as a colorless oil.

Workup

  1. customat 0° to 5° C
  2. customcondensed under reduced pressure

Sources & evidence

ORD record
ord-81e906a177134521bef3392ec281c3ae
Source dataset
uspto-grants-1980_01
Patent number
US04182757

Reaction notes

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