2-(2-Naphthoxy)ethanol → 2-(2-Naphthyloxy)ethyl methanesulfonate

HRID 2051892Notes

Reaction equation

HRID 2051892 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:12][CH2:13][OH:14].[CH3:15][S:16](Cl)(=[O:18])=[O:17].C(N(CC)CC)C>ClCCl>[CH3:15][S:16]([O:14][CH2:13][CH2:12][O:11][C:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)(=[O:18])=[O:17]

Participants

5

Reactant 3

HCID 71312-(2-Naphthoxy)ethanolHCID 8471TriethylamineHCID 31297Methanesulfonyl chloride

Product 1

HCID 190043832-(2-Naphthyloxy)ethyl methanesulfonate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

As described in Example 2, 13.5 g of 2-(2-naphthyloxy)ethanol in 400 ml of dichloromethane is reacted with 9.5 g of methanesulfonyl chloride in the presence of 11.4 g of triethylamine to give the product as tan crystals.

Sources & evidence

ORD record
ord-c77064d7c6a8497f83cbc3015820b13f
Source dataset
uspto-grants-1980_01
Patent number
US04182776

Reaction notes

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