Hydrochloric Acid → HCID 20378402, compound

HRID 2051900Notes

Reaction equation

HRID 2051900 reaction equation
[Cl:1][C:2]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:3]=1[O:4][CH2:5][CH2:6][NH:7][C:8]1[CH:18]=[CH:17][C:11]([C:12]([O:14]CC)=[O:13])=[CH:10][CH:9]=1.[OH-].[K+].C(O)C.Cl>O>[Cl:1][C:2]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:3]=1[O:4][CH2:5][CH2:6][NH:7][C:8]1[CH:18]=[CH:17][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14797Potassium HydroxideHCID 20378376Ethyl p-{[2-(2,4-dichlorophenoxy)ethyl]amino}benzoate

Product 1

HCID 20378402HCID 20378402, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 15 g of ethyl p-{[2-(2,4-dichlorophenoxy)ethyl]amino}benzoate and 15 g of potassium hydroxide in 200 ml. of 95% ethanol is refluxed for 3 hours. The solution is cooled, diluted with water, acidified with concentrated hydrochloric acid and filtered. The solid is recrystallized from ethanol to give crystals, mp 203°-205° C.

Workup

  1. temperatureThe solution is cooled
  2. filtrationfiltered
  3. customThe solid is recrystallized from ethanol
  4. customto give crystals, mp 203°-205° C.

Sources & evidence

ORD record
ord-6896fc87fd7a419380be695fe390ff4a
Source dataset
uspto-grants-1980_01
Patent number
US04182776

Reaction notes

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