Formic Acid → HCID 20378784, compound

HRID 2052129Notes

Reaction equation

HRID 2052129 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[P:11]([Cl:16])(Cl)(Cl)(Cl)[Cl:12].Cl.C(O)=[O:19]>C(Cl)(Cl)(Cl)Cl>[Cl:12][P:11]([Cl:16])([NH:6][C:4](=[O:5])[C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[CH3:1])=[O:19]

Participants

6

Reactant 4

HCID 284Formic AcidHCID 313Hydrochloric AcidHCID 107042-MethylbenzamideHCID 24819Phosphorus pentachloride

Product 1

HCID 20378784HCID 20378784, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture containing 48 g (0.36 mole) of 2-methylbenzamide, 74 g (0.36 mole) of phosphorus pentachloride and 500 ml of AR carbon tetrachloride was heated at 60°-70° for 30 min. at which time the HCl gas evolution had ceased. The solution was cooled to 30° and 16.9 g (0.36 mole) of 97% formic acid added dropwise. Stirring was continued following the addition for 40-50 min. The product was colleted, washed with AR carbon tetrachloride and air-dried to give 56 g, m.p. 91°-93°.

Workup

  1. temperatureThe solution was cooled to 30°
  2. additionthe addition for 40-50 min
  3. washwashed with AR carbon tetrachloride
  4. customair-dried
  5. customto give 56 g, m.p. 91°-93°

Sources & evidence

ORD record
ord-223b335de3094566b546b64e35ff7e04
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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