Formic Acid → HCID 54181364, compound

HRID 2052142Notes

Reaction equation

HRID 2052142 reaction equation
Cl.[CH:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([NH2:12])=[O:11])=[CH:4][CH:3]=1.[P:13]([Cl:18])(Cl)(Cl)(Cl)[Cl:14].C(O)=[O:20]>C(Cl)(Cl)(Cl)Cl>[Cl:14][P:13]([Cl:18])([NH:12][C:10](=[O:11])[CH:9]=[CH:8][C:5]1[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=1)=[O:20]

Participants

6

Reactant 4

HCID 284Formic AcidHCID 313Hydrochloric AcidHCID 24819Phosphorus pentachlorideHCID 5273472trans-Cinnamamide

Product 1

HCID 54181364HCID 54181364, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

Heated at 70° for 25 min. at which time the HCl gas evolution had ceased, a mixture of 59 g (0.4 mole) of cinnamide, 83.5 g (0.4 mole) of phosphorus pentachloride and 500 ml of AR carbon tetrachloride. After cooling to 30°, added dropwise, 19 g (0.4 mole) of 97% formic acid. Chilled to 0° and filtered. Air-dried to give 107.5 g, m.p. softens 82°, melts 83°-90°.

Workup

  1. temperatureAfter cooling to 30°
  2. additionadded dropwise
  3. temperatureChilled to 0°
  4. filtrationfiltered
  5. customAir-dried
  6. customto give 107.5 g
  7. customm.p. softens 82°
  8. custommelts 83°-90°

Sources & evidence

ORD record
ord-719c8a0fba5246908497e413958dd99b
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

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