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HRID2052257

反应详情

EQUATION

反应方程式

HRID 2052257 的结构方程式

REACTANTS

反应物

3
结构：SCc1ccc(Cl)cc1Cl
HCID95756

2,4-Dichlorotoluene-alpha-thiol

C7H6Cl2S

结构：[Na]
HCID5360545

Sodium

Na

结构：C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@@H]2OS(C)(=O)=O
HCID56609103

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@H]2SCc1ccc(Cl)cc1Cl
HCID22809847

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

To 1.04 gm. of sodium metal dissolved in 80 ml. of ethanol is added 5.55 ml. of 2,4-dichlorobenzylmercaptan followed by 1.5 gm. of 17β-methanesulfonyloxy-1,4-androstadiene-3,11-dione. Heat at reflux for 76 hours under an atmosphere of nitrogen. In a manner similar to that described in Example 1E, isolate the title compound.

WORKUP

后处理

  1. temperatureHeat
  2. temperatureat reflux for 76 hours under an atmosphere of nitrogen