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HRID2053801

反应详情

EQUATION

反应方程式

HRID 2053801 的结构方程式

REACTANTS

反应物

4
结构：CCNCC
HCID8021

Diethylamine

C4H11N

结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：O=C(NCc1nc2cc(Cl)ccc2[nH]1)c1ccc(C(=O)O)c(Cl)c1
HCID178523088

未命名化合物

PRODUCTS

生成物

1
结构：CCN(CC)C(=O)c1ccc(C(=O)NCc2nc3cc(Cl)ccc3[nH]2)cc1Cl
HCID178464200

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

Prepared analogously to Example 1d from 3-chloro-N-(5-chloro-1H-benzimidazol-2-ylmethyl)-4-carboxybenzamide, diethylamine, TBTU, and triethylamine in DMSO at ambient temperature. HPLC-MS results: retention time: 3.59 minutes; C20H20Cl2N4O2 (419.31); mass spectrum: (M+H)+=419.2.

WORKUP

后处理

  1. customHPLC-MS results