Ethyl Acetate → tert-Butyl 2-(6-(4-methylpiperazin-1-yl)nicotinamido)-4-(thiophen-2-yl)phenylcarbamate
Reaction equation
[CH3:30][N:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1.[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[c:10]([NH:20][C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[cH:11][cH:12][c:13](-[c:15]3[s:16][cH:17][cH:18][cH:19]3)[cH:14]2)[cH:28][cH:29]1>>[c:2]1([N:34]2[CH2:33][CH2:32][N:31]([CH3:30])[CH2:36][CH2:35]2)[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[c:10]([NH:20][C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[cH:11][cH:12][c:13](-[c:15]3[s:16][cH:17][cH:18][cH:19]3)[cH:14]2)[cH:28][cH:29]1Participants
4
Sources & evidence
- ORD record
- ord-b47b5cc3b14341608dca9cc82cbfc0eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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