HCID 69057349, compound → HCID 86606198, compound

HRID 2055222Notes

Reaction equation

HRID 2055222 reaction equation
[ClH:1].Cl.[CH2:3]([N:10]1[CH2:15][CH2:14][N:13]([CH2:16][C:17]([C:19]2[CH:24]=[CH:23][C:22]([N+:25]([O-])=O)=[CH:21][CH:20]=2)=[O:18])[CH2:12][CH2:11]1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>[Fe]>[ClH:1].[ClH:1].[ClH:1].[CH2:3]([N:10]1[CH2:11][CH2:12][N:13]([CH2:16][C:17]([C:19]2[CH:20]=[CH:21][C:22]([NH2:25])=[CH:23][CH:24]=2)=[O:18])[CH2:14][CH2:15]1)[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 1

HCID 69057349HCID 69057349, compound

Product 1

HCID 86606198HCID 86606198, compoundYield 60%

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

N1-benzyl-N4-(4-nitrophenacyl)piperazine dihydrochloride (IV-9) (2 mmol) was reduced by reductive iron in a procedure similar to Example 12 to give compound (IV-16), yield 60%, mp 286-288° C. M+ 309.

Workup

  1. customto give compound (IV-16), yield 60%, mp 286-288° C

Sources & evidence

ORD record
ord-c0bcef84032e48ae8e8a0a96b103cac0
Source dataset
uspto-grants-2008_02
Patent number
US07332495B2

Reaction notes

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