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HRID2055236

反应详情

EQUATION

反应方程式

HRID 2055236 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：COc1ccc2cc(C(=O)C(C)Br)ccc2c1Cl
HCID13699429

2-Bromo-1-(5-chloro-6-methoxy-2-naphthalenyl)-1-propanone

C14H12BrClO2

结构：CC(c1ccccc1)N1CCNCC1.Cl.Cl
HCID21537791

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc2cc(C(=O)C(C)N3CCN(CCc4ccccc4)CC3)ccc2c1Cl.Cl.Cl
HCID69200998

未命名化合物

收率 83.2%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A mixture of N-(1-phenylethyl)piperazine dihydrochloride (0.79 g, 3 mmol), 2-bromo-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one (1.64 g, 5 mmol) and K2CO3 (1.38 g, 10 mmol) in acetone was treated according to general preparation 2 to give 1.06 g of compound (IV-43) as white solid, yield 65%, mp 231-232° C. M+ 437.

WORKUP

后处理

  1. additionwas treated
  2. customaccording to general preparation 2