Ammonium → 1-[2-(2-Bromo-5-methoxy-4-methylphenyl)acetyl]-2-(4-fluorophenyl)-2,3-dihydropyridin-4-one
Reaction equation
[Br:21][c:22]1[c:23]([CH2:31][C:32](=[O:33])[OH:34])[cH:24][c:25]([O:29][CH3:30])[c:26]([CH3:28])[cH:27]1.[CH2:15]([Li:16])[CH2:17][CH2:18][CH3:19].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[Cl-:20].[Cl-:35].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[NH:9][CH:10]=[CH:11][C:12](=[O:14])[CH2:13]2)[cH:6][cH:7]1.[NH4+:36]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[N:9]([C:32]([CH2:31][c:23]3[c:22]([Br:21])[cH:27][c:26]([CH3:28])[c:25]([O:29][CH3:30])[cH:24]3)=[O:33])[CH:10]=[CH:11][C:12](=[O:14])[CH2:13]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9f67e3bc9136493898dbb3eee7c08730
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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