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HRID2057163

反应详情

EQUATION

反应方程式

HRID 2057163 的结构方程式

REACTANTS

反应物

7
结构：O=C(O)C1CCC1
HCID19494

Cyclobutanecarboxylic acid

C5H8O2

结构：BrCC1CC1
HCID81503

Bromomethylcyclopropane

C4H7Br

结构：CC(C)(C)[Si](C)(C)OC(C#CCO)C1(CC2CC2)CCC1
HCID66888884

未命名化合物

结构：OCC1(CC2CC2)CCC1
HCID66889412

未命名化合物

结构：O=CC1(CC2CC2)CCC1
HCID85825791

未命名化合物

结构：C#CC(O)C1(CC2CC2)CCC1
HCID86760617

未命名化合物

结构：C#CC(O[Si](C)(C)C(C)(C)C)C1(CC2CC2)CCC1
HCID86760618

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)C1(CC2CC2)CCC1
HCID45084786

1-(Cyclopropylmethyl)cyclobutane-1-carboxylic acid

C9H14O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described for Intermediate 15.1 from cyclobutanecarboxylic acid and (bromomethyl)cyclopropane. Intermediate 19.2: [1-(cyclopropylmethyl)cyclobutyl]methanol. The title compound was prepared according to the procedure described for Intermediate 15.2 from intermediate 19.1. Intermediate 19.3: 1-(cyclopropylmethyl)cyclobutanecarbaldehyde. The title compound was prepared according to the procedure described for Intermediate 15.3 from intermediate 19.2. Intermediate 19.4: 1-[1-(cyclopropylmethyl)cyclobutyl]prop-2-yn-1-ol. The title compound was prepared according to the procedure described for Intermediate 15.4 from intermediate 19.3. Intermediate 19.5: tert-butyl({1-[1-(cyclopropylmethyl)cyclobutyl]prop-2-ynyl}oxy) dimethylsilane. The title compound was prepared according to the procedure described for Intermediate 15.5 from intermediate 19.4. Rf 0.8 (EtOAc/hexanes 1/9). Intermediate 19.6: 4-{[tert-butyl(dimethyl)silyl]oxy}-4-[1-(cyclopropylmethyl) cyclobutyl]but-2-yn-1-ol.

WORKUP

后处理

  1. customThe title compound was prepared
  2. customThe title compound was prepared
  3. customThe title compound was prepared
  4. customThe title compound was prepared