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HRID2057303

反应详情

EQUATION

反应方程式

HRID 2057303 的结构方程式

REACTANTS

反应物

4
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：C1CCNCC1
HCID8082

Piperidine

C5H11N

结构：O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1
HCID2777399

4-(Trifluoromethyl)benzenesulfonyl chloride

C7H4ClF3O2S

结构：CN[C@H]1CC[C@H](CCCCOS(C)(=O)=O)CC1
HCID178484800

未命名化合物

PRODUCTS

生成物

1
结构：CN([C@H]1CC[C@H](CCCCN2CCCCC2)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1
HCID178484798

未命名化合物

PROCEDURE

实验过程

In analogy to examples 31.5 and 31.6, trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester.trifluoro-acetic acid and 4-trifluoromethyl-phenyl-sulfonylchloride were reacted, followed by treatment with piperidine to give trans-N-Methyl-N-[4-(4-piperidin-1-yl-butyl)-cyclohexyl]-4-trifluoromethyl-benzenesulfonamide, MS: 461 (MH+).