Isopropanol → HCID 20330162, compound

HRID 2057763Notes

Reaction equation

HRID 2057763 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([N+:10]([O-:12])=[O:11])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1.[C:20](OC(=O)C)(=[O:22])[CH3:21].C(O)(C)C>O>[C:20]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([N+:10]([O-:12])=[O:11])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1)(=[O:22])[CH3:21]

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 7918Acetic AnhydrideHCID 20330193HCID 20330193, compound

Product 1

HCID 20330162HCID 20330162, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a 0.33 g. sample of 5-amino-2-nitro-3-phenylbenzofuran is added 1 ml. of acetic anhydride, and the mixture is heated for 5 minutes on a steam bath. About 10 ml. of isopropanol is added, and the mixture is again heated on a steam bath to dissolve the solid. It is then saturated with hot water and cooled to provide yellow needles of 5-acetamido-2-nitro-3-phenylbenzofuran, m.p. 204°-207° C.

Workup

  1. temperaturethe mixture is again heated on a steam bath
  2. dissolutionto dissolve the solid

Sources & evidence

ORD record
ord-52031e06250340e29a3aaf85c354b506
Source dataset
uspto-grants-1980_07
Patent number
US04212865

Reaction notes

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