5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one → HCID 20329396, compound

HRID 2057904Notes

Reaction equation

HRID 2057904 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6](Cl)=[O:7].[N:9]1[C:14]2[NH:15][C:16]3[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=3[C:18](=[O:20])[NH:19][C:13]=2[CH:12]=[CH:11][CH:10]=1>C1(C)C(C)=CC=CC=1>[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]([N:15]1[C:16]2[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=2[C:18](=[O:20])[NH:19][C:13]2[CH:12]=[CH:11][CH:10]=[N:9][C:14]1=2)=[O:7]

Participants

4

Reactant 2

HCID 701695,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-oneHCID 740895-Chlorovaleryl chloride

Product 1

HCID 20329396HCID 20329396, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A solution of 5-chlorovaleryl chloride and 5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one in xylene was reacted to obtain 11-(5-chlorovaleryl)-5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one which after crystallization from n-propanol melted at 170°-172° C.

Sources & evidence

ORD record
ord-2f44f8667f774bb69c2f4c5092b270fb
Source dataset
uspto-grants-1980_07
Patent number
US04213985

Reaction notes

Loading…