反应详情

温度

100 °C

10 g of p-hydroxybenzophenone are dissolved in 100 ml of dimethylformamide. 8.3 g of 2-chloroethylcarbamic acid ethyl ester and 13.8 g of potassium carbonate are added to the solution and the mixture is warmed to 100° C. and maintained there for 3 hours with stirring. The mixture is poured onto an ice/water bath. The resulting crystals are filtered and washed with water. The crystalline substance is dried at 40° C. in a vacuum drying oven. Recrystallization once from ether yields 12.5 g (80%) of 2-(p-benzoylphenoxy)ethylcarbamic acid ethyl ester, m.p.--84°-86° C.

1. temperaturemaintained there for 3 hours
2. additionThe mixture is poured onto an ice/water bath
3. filtrationThe resulting crystals are filtered
4. washwashed with water
5. customThe crystalline substance is dried at 40° C. in a vacuum
6. customdrying oven
7. customRecrystallization once from ether