Sulfuric Acid → HCID 70549270, compound

HRID 2058794Notes

Reaction equation

HRID 2058794 reaction equation
[Na].O[CH:3]=[CH:4][C:5]#[N:6].[NH:7]1[CH2:11][CH2:10][CH2:9][CH2:8]1.S(=O)(=O)(O)O>C(O)C>[NH:7]1[CH2:11][CH2:10][CH:9]([CH:3]=[CH:4][C:5]#[N:6])[CH2:8]1

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 31268PyrrolidineHCID 86738287Sodium 3-hydroxyacrylonitrile

Product 1

HCID 70549270HCID 70549270, compoundYield 79.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
50 °C

Procedure

32.5 g (0.25 mol) of sodium-3-hydroxyacrylonitrile (content 70%) is added to a mixture of 17.8 g (0.25 mol) of pyrrolidine, 12.3 g (0.125 mol) of sulfuric acid and 200 ml of ethanol, and the mixture is stirred at 50° C. for 7 h. After working up as in Example 50, 24.3 g of 3-pyrrolidine acrylonitrile (79.6%) is obtained.

Sources & evidence

ORD record
ord-f4ff8d10492346a7bd980617bc8eed74
Source dataset
uspto-grants-1982_03
Patent number
US04319024

Reaction notes

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