2-Methoxybenzaldehyde → 2-(2-Methoxyphenyl)oxirane

HRID 2058997Notes

Reaction equation

[H-].[Na+].[I-].[CH3:4][S+](C)C.[CH3:8][O:9][C:10]1[CH:17]=[CH:16][CH:15]=[CH:14][C:11]=1[CH:12]=[O:13]>>[CH3:8][O:9][C:10]1[CH:17]=[CH:16][CH:15]=[CH:14][C:11]=1[CH:12]1[O:13][CH2:4]1

Participants

Reactant 3

HCID 86582-Methoxybenzaldehyde

HCID 24758Sodium hydride

HCID 75127Trimethylsulfonium iodide

Product 1

HCID 113555722-(2-Methoxyphenyl)oxirane

Procedure

A mixture of 9.7 g of sodium hydride, 38 g of trimethylsulfonium iodide and 25.2 g (0.185 mol) of o-methoxybenzaldehyde is reacted to give o-methoxystyrene oxide.

Workup

customis reacted

Sources & evidence

ORD record: ord-245e84ff09894a19b0ea49d288f204ba
Source dataset: uspto-grants-1982_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04321195

Reaction notes

Loading…