Methyl iodide → tert-butyl N-(2-chloro-3-methylfuro[2,3-c]pyridin-7-yl)-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate

HRID 205901Notes

Reaction equation

HRID 205901 reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:27][CH:28]([N-:29][CH:30]([CH3:31])[CH3:32])[CH3:33].[CH3:34][I:35].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([N:10]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[n:7][cH:8][cH:9]2)[o:25]1.[Li+:26]>>[Cl:1][c:2]1[c:3]([CH3:27])[c:4]2[c:5]([c:6]([N:10]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[n:7][cH:8][cH:9]2)[o:25]1

Participants

6

Reactant 5

HCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 66760259HCID 66760259, compound

Product 1

HCID 66760298tert-butyl N-(2-chloro-3-methylfuro[2,3-c]pyridin-7-yl)-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate

Sources & evidence

ORD record
ord-d6b2338fea0b4a3787c7ac9e6931e3bb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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